* Corresponding author Phone: 교신저자 연락처 Fax: 교신저자 팩스번호 E-mail: 교신저자 이메일주소	This is an open-access journal distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/)

https://doi.org/10.15433/ksmb.2000.0.0.000                                                  ISSN 2383-5400 (Online)

한글제목

Title

저자명1, 저자명2, 저자명2, 교신저자2*

Author1, Author2, Author2, Corresponding author2*

1직위, 소속, 지역, 우편번호, 국가 (국문) (직위는 대학원생/박사후연구원/교수, 연구원/선임연구원/책임연구원 등으로 표기)

2직위, 소속, 지역, 우편번호, 국가 (국문)

1Affiliation, City Postal code, Country

2Affiliation, City Postal code, Country

† Both authors contributed equally to this work (공동제1저자의 경우 저자명 뒤에 †표기)

(Received day month year, Revised day month year, Accepted day month year)

Abstract    영문으로 200 words 이내

Keywords : 영문으로 5개 이내

서  론

J. Mar. Biosci. Biotechnol. 2000, p. 00 - 00                                   Vol. X, No. X [Research Paper/Note/Review]

논문의 전개에 필요한 논리나 연구가 이루어진 배경 등을 밝히는데 필요한 정보를 기술하되 필요이상의 총론적 서술로 된 서론은 가급적 피한다.

재료 및 방법

1. 소제목

1.1. 소제목

다른 연구자들이 실험을 반복해서 행할 수 있도록 상세하게 기술한다. 다만 잘 알려진 방법 등을 채택한 경우에는 서술을 피하고 참고 문헌 등으로 출처를 분명하게 밝힌다 [1].

결  과

연구의 논리 전개 순서에 따라 얻어진 결과를 설명한다.

고  찰

얻어진 결과로부터 결론을 도출해내며 결과의 중요성 등을 언급하며 본문에 인용된 연구 결과들과 비교 설명하거나 앞으로의 연구를 위해 고려해야할 사항들에 대하여 정리하여 설명한다.

결  론

논문의 결과를 간결하게 작성한다.

감사의 글

연구비의 출처나 연구를 위해 도움을 준 개인 또는 기관에 대해 감사의 표시를 한다. 단, 너무 과도하거나 지나친 표현은 삼간다.

Figure 1. figure caption

Table 1. table caption

그림(Figure), 표(Table), 아미노산, DNA, RNA의 염기서열은 직접 복사, 인쇄가 가능하도록 작성한다. 사진은 명암이 뚜렷하여야 하며 전자현미경 사진의 경우 축적도를 나타낼 수 있는 실제 거리를 사진 내에 포함시켜야한다. 모든 표(Table)와 그림(Figure)은 반드시 영문으로 작성한다. Table의 제목은 내용의 상단에, Figure의 제목은 내용의 하단에 작성하며 언급되는 본문내용에 배치한다.

References

1. Hodson, L., Rosqvist, F., Parry, S. A. 2020. The influence of dietary fatty acids on liver fat content and metabolism. Proc. Nutr. Soc. 79, 30-41.

2. Westerterp, K. R. 2018. Exercise, energy balance and body composition. Eur. J. Clin. Nutr. 72, 1246-1250.

3. Peyton, K. J., Liu, X .M., Shebib, A. R., Johnson, F. K., Johnson, R. A., Durante, W. 2018. Arginase inhibition prevents the development of hypertension and improves insulin resistance in obese rats. Amino Acids 50, 747–754.

4. Koenen, M., Hill, M. A., Cohen, P., Sowers, J. R. 2021. Obesity, adipose tissue and vascular dysfunction. Circ. Res. 128, 951-968.

5. Dias, S., Paredes, S., Ribeiro, L. 2018. Drugs Involved in dyslipidemia and obesity treatment: Focus on adipose tissue. Int. J. Endocrinol. 2018, 2637418.

6. Rajjo, T., Mohammed, K., Alsawas, M., Ahmed, A. T., Farah, W., Asi, N., Almasri, J., Prokop, L. J., Murad, M. H. 2017. Treatment of pediatric obesity: An umbrella systematic review. J. Clin. Endocrinol. Metab. 102, 763-775.

7. Kumar, A., Chauhan, S. 2021. Pancreatic lipase inhibitors: The road voyaged and successes. Life Sci. 271, 119115.

8. Narayanaswami, V., Dwoskin, L. P. 2017. Obesity: Current and potential pharmacotherapeutics and targets. Pharmacol. Ther. 170, 116-147.

9. Siebenhofer, A., Jeitler, K., Horvath, K., Berghold, A., Posch, N., Meschik, J., Semlitsch, T. 2016. Long-term effects of weight-reducing drugs in people with hypertension. Cochrane. Database Syst. Rev. 3, CD007654.

10. Krentz, A. J., Fujioka, K., Hompesch, M. 2016. Evolution of pharmacological obesity treatments: focus on adverse side-effect profiles. Diabetes Obes. Metab. 18, 558-570.

11. Desmedt, B., Courselle, P., De Beer, J. O., Rogiers, V., Grosber, M., Deconinck, E., De Paepe, K. 2016. Overview of skin whitening agents with an insight into the illegal cosmetic market in Europe. J. Eur. Acad. Dermatol. Venereol. 30, 943–950.

12. Qian, W., Liu, W., Zhu, D., Cao, Y., Tang, A., Gong, G., Su, H. 2020. Natural skin-whitening compounds for the treatment of melanogenesis (Review). Exp. Ther. Med. 20, 173-185.

13. Costin, G. E., Hearing, V. J. 2007. Human skin pigmentation: Melanocytes modulate skin color in response to stress. FASEB J. 21, 976–994.

14. Ohbayashi, N., Fukuda, M. 2020. Recent advances in understanding the molecular basis of melanogenesis in melanocytes. F1000Res 9 F1000.

15. Pillaiyar, T., Manickam, M., Jung, S. H. 2017. Recent development of signaling pathways inhibitors of melanogenesis. Cell. Signal. 40, 99-115.

16. Pillaiyar, T., Namasivayam, V., Manickam, M., Jung, S. H. 2018. Inhibitors of melanogenesis: An updated review. J. Med. Chem. 61, 7395-7418.

17. Smit, N., Vicanova, J., Pavel, S. 2009. The hunt for natural skin whitening agents. Int. J. Mol. Sci. 10, 5326–5349.

18. Draelos, Z. D. 2007. Skin lightening preparations and the hydroquinone controversy. Dermatol. Ther. 20, 308–313.

19. Ramos-Romero, S., Torrella, J. R., Pagès, T., Viscor, G., Torres, J. L. 2021. Edible microalgae and their bioactive compounds in the prevention and treatment of metabolic alterations. Nutrients 13, 563.

20. Thiyagarasaiyar, K., Goh, B. H., Jeon, Y. J., Yow, Y. Y. 2020. Algae metabolites in cosmeceutical: An overview of current applications and challenges. Mar. Drugs 18, 323.

21. Muhamad, I. I., Zulkifli, N., Selvakumaran, S. A., Lazim, N. A. M. 2019. Bioactive algal-derived polysaccharides: Multi-functionalization, therapeutic potential and biomedical applications. Curr. Pharm. Des. 25, 1147-1162.

22. Wan-Loy, C., Siew-Moi, P. 2016. Marine algae as a potential source for anti-obesity agents. Mar. Drugs 14, 222.

23. Sanjeewa, K. K. A., Lee, W., Jeon, Y.-J. 2018. Nutrients and bioactive potentials of edible green and red seaweed in Korea. Fish. Aquat. Sci. 21, 19.

24. Kim, E., Cui, J., Kang, I., Zhang, G., Lee, Y. 2021. Potential antidiabetic effects of seaweed extracts by upregulating glucose utilization and alleviating inflammation in C2C12 myotubes. Int. J. Environ. Res. Public Health 18, 1367.

25. Monmai, C., Rod-In, W., Jang, A. Y., Lee, S. M., Jung, S. K., You, S., Park, W. J. 2020. Immune-enhancing effects of anionic macromolecules extracted from Codium fragile coupled with arachidonic acid in RAW264.7 cells. PLoS One 15, e0239422.

26. Lee, C., Park, G. H., Ahn, E. M., Kim, B. A., Park, C. I., Jang, J. H. 2013. Protective effect of Codium fragile against UVB-induced pro-inflammatory and oxidative damages in HaCaT cells and BALB/c mice. Fitoterapia 86, 54-63.

27. Lee, S. A., Moon, S. M., Choi, Y. H., Han, S. H., Park, B. R., Choi, M. S., Kim, J. S., Kim, Y. H., Kim, D. K., Kim, C. S. 2017. Aqueous extract of Codium fragile suppressed inflammatory responses in lipopolysaccharide-stimulated RAW264.7 cells and carrageenan-induced rats. Biomed. Pharmacother. 93, 1055-1064.

28. Kang, C. H., Choi, Y. H., Park, S. Y., Kim, G. Y. 2012. Anti-inflammatory effects of methanol extract of Codium fragile in lipopolysaccharide-stimulated RAW 264.7 cells. J. Med. Food. 15, 44-50.

29. Kolsi, R. B. A., Jardak, N., Hajkacem, F., Chaaben, R., Jribi, I., Feki, A. E., Rebai, T., Jamoussi, K., Fki, L., Belghith, H., Belghith, K. 2017. Anti-obesity effect and protection of liver-kidney functions by Codium fragile sulphated polysaccharide on high fat diet induced obese rats. Int. J. Biol. Macromol. 102, 119-129.

30. Le Lay, S., Dugail, I. 2009. Connecting lipid droplet biology and the metabolic syndrome. Prog. Lipid Res. 48, 191-195.

31. Padilla-Benavides, T., Velez-delValle, C., Marsch-Moreno, M., Castro-Muñozledo, F., Kuri-Harcuch, W. 2016. Lipogenic enzymes complexes and cytoplasmic lipid droplet formation during adipogenesis. J. Cell Biochem. 117, 2315-2326.

32. Yang, X., Heckmann, B. L., Zhang, X., Smas, C. M., Liu, J. 2013. Distinct mechanisms regulate ATGL-mediated adipocyte lipolysis by lipid droplet coat proteins. Mol. Endocrinol. 27, 116-126.

33. Ali, A. T., Hochfeld, W. E., Myburgh, R., Pepper, M. S. 2013. Adipocyte and adipogenesis. Eur. J. Cell Biol. 92, 229-236.

34. Spiegelman, B. M., Flier, J. S. 2001. Obesity and the regulation of energy balance. Cell 104, 531–543.

35. Muruganandan, S., Ionescu, A. M., Sinal, C. J. 2020. At the crossroads of the adipocyte and osteoclast differentiation programs: Future therapeutic perspectives. Int. J. Mol. Sci. 21, 2277.

36. Rosen, E. D., Walkey, C. J., Puigserver, P., Spiegelman, B.M. 2020. Transcriptional regulation of adipogenesis. Genes Dev. 14, 1293–1307.

37. Serre, C., Busuttil, V., Botto, J. M. 2018. Intrinsic and extrinsic regulation of human skin melanogenesis and pigmentation. Int. J. Cosmet. Sci. 40, 328-347.

38. Rzepka, Z., Buszman, E., Beberok, A., Wrześniok, D. 2016. From tyrosine to melanin: Signaling pathways and factors regulating melanogenesis. Postepy Hig. Med. Dosw (Online). 70, 695-708.

39. D'Mello, S. A., Finlay, G. J., Baguley, B. C., Askarian-Amiri, M. E. 2016. Signaling pathways in melanogenesis. Int. J. Mol. Sci. 17, 1144.

40. Wan, P., Hu, Y., He, L. 2011. Regulation of melanocyte pivotal transcription factor MITF by some other transcription factors. Mol. Cell. Biochem. 354, 241-246.

41. Schallreuter, K. U. 2007. Advances in melanocyte basic science research. Dermatol. Clin. 25, 283-291,

「한국해양바이오학회지」저작권 이양동의서

한국해양바이오학회지는 open-access 저널로 온라인으로 출판됩니다.

제 목	(국문)
	(영문)
COPYRIGHT TRANSFER FORM Please complete and sign this form. It is required to obtain a written confirmation from authors in order to acquire copyrights for papers published in Journal of Marine Bioscience and Biotechnology. Title of Manuscript : _______________________________________________________________________________ Name of All Authors : _____________________________________________________________________________ Copyright to the above-listed unpublished and original article submitted by the above author(s) is hereby transferred to the The Korean Society for Marine Biotechnology for the full term thereof throughout the world, and to acceptance of the article for publication in Journal of Marine Bioscience and Biotechnology. By signing this Agreement, the author(s) represent and warrant that the article is original with the author(s) and does not infringe any copyright or violate any other right of any third parties, and that the article has not been published elsewhere, and is not being considered for publication elsewhere in any form, except as provided herein. If each author’s signature does not appear below, the signing author(s) represent that they sign this Agreement as authorized agents for and on behalf of all the authors, and that this Agreement and authorization is made on behalf of all the authors. Author Signature(s) : ____________________________________________
투고된 논문에 대하여 심사 가능한 심사위원 3～5인을 추천바랍니다. (성명,소속,이메일) 1. 2. 3. 4. 5.